Bubonic plague is one of the most devastating diseases in history, having killed around 100 million people during the ‘Black Death’ in the 14th century.
Drawings and paintings from the outbreak, which wiped out about a third of the European population, depict town criers saying ‘bring out your dead’ while dragging trailers piled with infected corpses.
It is caused by a bacterium known as Yersinia pestis, which uses the flea as a host and is usually transmitted to humans via rats.
Drawings and paintings from the outbreak, which wiped out about a third of the European population, depict town criers saying ‘bring out your dead’ while dragging trailers piled with infected corpses
The disease causes grotesque symptoms such as gangrene and the appearance of large swellings on the groin, armpits or neck, known as ‘buboes’.
It kills up to two thirds of sufferers within just four days if it is not treated, although if antibiotics are administered within 24 hours of infection patients are highly likely to survive.
After the Black Death arrived in 1347 plague became a common phenomenon in Europe, with outbreaks recurring regularly until the 18th century.
Bubonic plague has almost completely vanished from the rich world, with 90 per cent of all cases now found in Africa.
However, there have been a few non-fatal cases in the U.S. in recent years, while in August 2013 a 15-year-old boy died in Kyrgyzstan after eating a groundhog infected with the disease.
Three months later, an outbreak in a Madagascan killed at least 20 people in a week.
A year before 60 people died as a result of the infection, more than in any other country in the world.
Outbreaks in China have been rare in recent years, and most have happened in remote rural areas of the west.
China’s state broadcaster said there were 12 diagnosed cases and three deaths in the province of Qinghai in 2009, and one in Sichuan in 2012.
In the United States between five and 15 people die every year as a result, mostly in western states.